Installation and configuration instructions for Bayesian Network Wizard
(see Ferrazzi et al., Bioinformatics, 2009)
Contact: fulvia.ferrazzi@unipv.it

The compiled software and source files can be downloaded from 
http://aimed11.unipv.it/BayesianNetworkWizard under the terms of 
GNU Library GPL version 2.

Please note that the software incorporates the Bayesian Network Toolbox 
from K. Murphy (http://people.cs.ubc.ca/~murphyk/Software/BNT/bnt.html), 
which is also released under the GNU Library GPL version 2. 


Bayesian Network Wizard (BNW) distribution.
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The following files can be downloaded from the BNW web site:

- Readme.txt (this file): installation and configuration instructions.
  
- License.txt: Terms and Conditions of Use (GNU Library GPL v.2) 

- BNW1-1-WIN.zip: tool compiled for Windows platforms

- BNW_sourcefiles.zip: source files (Matlab) of the application 

- trial_datasets.zip: example datasets to use with the software tool

- Tutorial.pdf: brief guide to the use of the tool


How to install the compiled BNW (the program requires the user to install the 
MATLAB runtime libraries that are distributed together with the BNW files):
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1) Download the distribution file BNW1-1-WIN.zip

2) Extract all files from the zip file

3) Install the MATLAB libraries running the MCRInstaller.exe (if the same 
   version of the MATLAB library files are not already installed)

   The following directory should be automatically added to your system path:    
   <MCR_root>\<version>\runtime\win32

   Note. If you have already installed MATLAB on your machine there is a 
   limitation regarding directories on your path: this tool requires that 
   MCR_root directory is first on the path, MATLAB requires that the 
   matlabroot directory is first on the path.

4) Run for the first time the Bayes executable file (Bayes.exe) and close
   the application. In this step the Bayes_mcr directory and its subdirectories 
   are created.

5) Run again the Bayes executable file and try with any of the trial data sets
   distributed in the zip file:

   - expressiondata.txt and expressiondata_discrete.txt: temporal expression 
     values (respectively continuous and discretized) of 20 cell cycle genes. 
     The gene names are in genenames.txt
  
   - SNPdata.txt: measured values for 45 SNPs and a binary phenotype. Missing 
     data are indicated as NA.